People with a history of certain conditions, such as recent inflammatory cardiac illnesses (e.g., myocarditis, pericarditis, endocarditis) within the past 6 months, acute rheumatic fever with active myocardial inflammation, or acute decompensated heart failure, can receive the Pfizer vaccine. However, it is crucial to consult with a GP, immunisation specialist, or cardiologist to determine the optimal timing for vaccination and to discuss any additional precautions that may be recommended based on individual health circumstances.

People with weakened immune systems (immunocompromise) due to medical conditions or immunosuppressive medications, are strongly recommended to receive the COVID-19 vaccination by the Australian Government. The Pfizer vaccine is deemed safe for those with immunocompromise.

People who are immunocompromised, including those with conditions like HIV, face a heightened risk of severe illness and increased mortality from COVID-19. While clinical trials for Pfizer did not extensively include people with immunocompromise, except for a small group with stable HIV, it is uncertain whether Pfizer's effectiveness is comparable in this group compared to the general population. As a precaution, maintaining other preventive measures like physical distancing is advised even after vaccination in individuals with immunocompromise.

Pregnant women are routinely recommended to receive Pfizer or Moderna at any stage of pregnancy. Trying to become pregnant does not necessitate delaying vaccination, and there's no need to avoid pregnancy after vaccination.

The increased risk of severe illness and adverse pregnancy outcomes for pregnant women with COVID-19 enhances the importance of vaccination. Real-world evidence supports the safety of Pfizer for pregnant and breastfeeding women, with no need to stop breastfeeding after vaccination.

The Australian Technical Advisory Group on Immunisation (ATAGI) advises:

• Pregnant individuals can receive the Pfizer vaccine at any stage of pregnancy.
• Trying to become pregnant doesn't require delaying vaccination.
• Pfizer is safe for pregnant and breastfeeding individuals.
• If Pfizer isn't an option, discussing the suitability of the Novavax vaccine with a doctor is recommended.

Unvaccinated pregnant women face a higher risk of severe COVID-19 illness, potentially impacting premature birth risks. COVID-19 vaccination may provide protection to babies through antibody transfer via the placenta during pregnancy or breast milk during breastfeeding.

If you have previously had COVID-19, it's important to inform your immunisation provider. Vaccination can be postponed for up to six months after the acute illness, as evidence indicates reduced reinfection risk during this period. However, vaccination is permissible once you have recovered from symptomatic infection. If you are considering being vaccinated earlier than six months, you will need to discuss this decision with your doctor or immunisation provider. If you're experiencing ongoing illness from COVID-19, consult your treating doctor to determine the optimal timing for vaccination.

The Pfizer vaccine has received provisional approval for individuals aged 5 years and older but is not authorised for those aged 4 and under. Extensive clinical trials have proven its efficacy for people aged 12 and above. Recent research confirms its safety and effectiveness for children aged 5-11, with a notable 95% reduction in symptomatic COVID-19 cases after two doses. This effectiveness spans diverse demographics, including those over 65 and individuals with pre-existing medical conditions. Booster doses are currently recommended five months after the second dose.